Why do i get I/O Bus Resets in my SAN environment?

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First thing you should do is examine every single client, that also belongs to your "backup" SAN-zone! Examine all scheduled tasks! If you're backing up Win2K Clients be 100% sure to disable the removable storage manager service (RSM)! The RSM tries to query your backup-devices and collides with the concurrent access of your backupserver or storagenodes.